What's the harm? Well, there is a non-zero chance of forgetting to set mixture back to full rich for takeoff.
I didn't see anyone touch on this (sorry if I missed it, but it is not what's the harm, but what's the benefit? There's a huge benefit for not fouling your plugs! With any engine, even if "properly" set up, you run the risk of one (or more) cylinders being on the very rich side and occasionally fouling the plugs. If after startup you AGGRESSIVLY lean, you will not get fouled plugs. As for forgetting to go full rich, if you really lean, the engine will never get close to Takeoff Power and won't even get to enough power to hurt anything.
I'm sure you can find lots of videos on this, and if you want, I'm sure you could find someone that believes in the process to show you. Basic process is:
- Start the engine and start to lean. Pending the temperature (winter, etc.), you may only get a couple of turns before the engine starts to stuble.
- Let the engine warm up as you set up radios, etc.
- Prior to Taxi, set a normal idle (not the slowest you can do, but what you normally "idle" at.
- Lean the engine until it stumbles and *slightly* enrichen so the engine runs smoothly.
- Then Taxi normally.
The first time, taxi as needed out onto the ramp (or the Runup Area) where there is no one behind you and start to do a Runup. You may, or may not, get to your normal Runup power. If you do, push it a little further, and you should not get anywhere near Takeoff power. If you do, you didn't lean enough. Go back down to idle and lean some more and try it again. Once you get the process down, it is easy to repeat. (In my plane I can get to Runup Power, but that's about it. I really can't get much more power than that.)