My wife and I have done it fairly extensively in the C206. With the front seats forward we put luggage on the seats and have lots of room to sleep comfortably in the cabin. On our
first Vermont to Alaska trip we spent almost every night of the five weeks sleeping in the plane after realizing that pitching a tent was a waste of time and that getting off the ground in a tightly sealed cabin was all around much more comfortable, especially in chilly conditions. At the time, FBOs were very accomodating and we had access to bathrooms and showers as well. It was actually fairly "luxurious" under the circumstances.
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Other pictures of a second trip included in
this link, which also describes an attempt I made to fly back to Alaska on straight floats in a PA12. Not that I actually ever needed it but I had configured the rear space to have available if I got stuck on a lake in the wilderness on the way, with the plan in that case to fill a duffel bag with rocks as an anchor, paddle out to the middle of the lake and sleep in the rear space until I could be rescued. The main concern in that case was bears coming out of hibernation. It wouldn't have been particularly comfortable, but that wasn't the point.
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