I don't recall the actually FAA regs, but I follow the idea he says. Many OTC allergy meds make me sleepy, balloon headed, and really affect my cognitive skills. So if I take one or two for a day's relief, I self-ground for at least 2 or three days afterwards.
For OTC meds that affect cognition or cause drowsiness, there is no need to get the AME involved or declare to OKC. Just provide enough stand down time to metabolize all of the drug and have none left in your system.
For prescription drugs that mess with your head, then it's time to ask the AME what you need to know and declare and when to do it. Different meds have different rules. Also depending on the individual medication or the cocktail, FAA medical is gonna what to know the underlying reason they are being prescribed.
The standards (what ever the correct ones are versus my good natured guessing) apply to all "classes of physicals". So just because you hold a Class 3 medical does not mean you can skate on something a Class 1 is being hammered on.