Why pills?... In the past I've crushed them or taken them with yogurt....
I would advise against crushing pills (especially if it is prescription medication), unless you have consulted with a doctor, and the doctor approves that you crush the pills.
Having medicine in a pill form, is often too buffer/control/slow/meter how fast the medicine is absorbed, and how fast it breaks down in your digestive tract.
Sometimes if you crush pills, it can allow medicine to be absorbed to quickly.
On the other end of the spectrum, sometimes the body is only capable of absorbing so much medicine at a time. So sometimes if you crush a pill, it can allow the ingredients to break down before they have a chance to being properly absorbed.
So crushing some pills can sometimes give you a short-term overdose. Sometimes on the other edge of the spectrum, crushing pills can reduce their effectiveness.
Sometimes if I have a sudden severe headache or chest pain, I will chew aspirin, in case it's a heart attack or stroke. (I'm not a licensed doctor or licensed pilot.

) Chewing aspirin, can more quickly thin the blood. However it also can do damage to tooth enamel, and increase risk of G.I. bleeding.
If you are getting prescription medications, you should ask your doctor and/or pharmacist, read labels and pamphlets to make sure what if any types of food to avoid, and if they should be taken with meals or on an empty stomach. You should also let your doctor and/or pharmacist know of any other medications or supplements you are taking.
Milk (yogurt), pop, antacids, citrus; often neutralize or reduce the effectiveness of many drugs.
My wife takes a thyroid medication. She's not allowed to eat 4 hours before or eat for 1 hour after eating. So we have to schedule meals and her medicine in a way that her medicine will be effective.