Some pf the Van's guys are pretty extreme with LOP...to the point of running WOT all the time and adjusting rpm with mixture alone.
I'm like you in that I use fuel flow as a cross check. Performance cruise is about 2550-2600 rpm (FP prop) and fuel flow is right at about 7 gph when leaned nicely. But it's the CHTs that I'm really monitoring the most. If I'm 150 degrees ROP, the consumption balloons up to 9.5-10 gph at the same settings. I'm too chicken to go LOP at anything below 8000' DA, but a lot of guys do.