When my airplane was pretty new to me, and I first bought a digital CO detector, I took some friends flying one day. One of them was a bit chilly, and closed off the cabin air vents while I wasn't looking, which apparently caused some carbon monoxide to accumulate in the cabin. When my detector alerted, I landed and had a shop check the exhaust system for leaks before we decided there was nothing there that should keep us from continuing home.
Later on, I chased the leak for months before I gave up on it. That included plugging every gap in the firewall, replacing all of the cabin and baggage door and window seals, replacing some window sealant that was cracking, and even duct taping all of the floor panels and the tail cone. I even let one shop talk me into replacing my entire exhaust system at considerable expense, which I now know to have been wholly unnecessary, and am pretty embarrassed about having done. (Luckily, the after-market exhaust system for the 210 is actually a useful upgrade to do anyway.)
In the end, having fixed every conceivable problem, I now fly with a bit of cabin air, and the positive pressure does just fine to keep the CO out of wherever it's coming from. I keep the digital detector going to monitor, and I'm very comfortable with that. I've come to learn that it isn't an uncommon thing. The digital detectors are all a lot more sensitive than the junk "CO detectors" made of cardboard, not to mention the household CO detectors that keep us alive at home.
This isn't to say at all that you shouldn't take it seriously—especially if something has recently changed—but I just thought I would share. IMO the single best thing you can do is velcro your CO detector to the panel and turn it on every time you fly.