Dayum...I guess I am just too new a pilot to ever consider doing that.
A good friend (who owns several airplanes and a helicopter and has thousands of hours of flight time) once told me that if you have no where to go in a hurry, fly a GA plane.
Of course I know what he meant by that....be prepared to land and wait the weather out if it is bad. Do NOT make definitive plans..if you have to do that, drive.