There's Creve Coeur off to the west a bit with plenty of restaurants and junk in between. Heck, it's probably non-stop everything by these days.
St. Louis Downtown in Cahokia is a nice little airport, very well kept. But, there's no dang easy or fast way to get in and out of there from the ground.
The train system was being expanded at a pretty good pace last I was there. It should get ya around fairly well between STL, downtown, West End and other places between those and the airport.
Enjoy your time while up there. I was born and raised in that city, watching the Arch pop up from my backyard in north St. Louis.